Reaction ofp-Nitrophenyl Benzenesulfonates with Thiophenoxides
نویسندگان
چکیده
منابع مشابه
The reaction of p-nitrophenyl esters with chymotrypsin and insulin.
was discussed. This compound is a member of a group of organophosphorus insecticides which are powerful inhibitors of cholinesterases. They will also inhibit chymotrypsin, and it has been shown that this inhibition is due to combination of the compounds with a single active centre in the enzyme (Jansen, Nutting & Balls, 1949; Hartley & Kilby, 1952).We investigated the reaction ofchymotrypsin wi...
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1. The steady-state rate of hydrolysis of 2,4-dinitrophenyl phosphate catalysed by Escherichia coli phosphatase is identical with that of 4-nitrophenyl phosphate over the pH range 5.5-8.5. 2. The increase in the rate of the enzyme-catalysed decomposition of nitrophenyl phosphates in the presence of tris at pH8.1 and 5.9 is consistent with the hypothesis that tris increases the rate of decomposi...
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The inhibition of proteolytic enzymes by organophosphorus compounds has been extensively studied in recent years (1, 2). Such studies have shown that the reaction of trypsin with diisopropyl fluorophosphate (3) or diethyl p-nitrophenyl phosphate (DENP) (4) is accompanied by a loss in the proteolytic, esterase, and amidase activities of this enzyme. It is not certain, however, whether these inhi...
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5. Release of these materials from mycelium treated with fatty acid was greatest at acid pH values, but change of pH had no significant effect upon the release by detergents. 6. Incubation of mycelial pads of these fungi in the presence ofarsenite leads to the accumulation of pyruvate and ax-oxoglutarate together with traces of an unidentified a-keto acid. The yield of ca-keto acids is increase...
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ژورنال
عنوان ژورنال: Bulletin of the Chemical Society of Japan
سال: 1969
ISSN: 0009-2673,1348-0634
DOI: 10.1246/bcsj.42.2894